Thus the MEC is the substance of the interstitial (intercellular) medium. In particular the ECM has significant roles in normal tissue development, function and disease. The MEC is a physiological integration medium, of a complex biochemical nature, in which the cells are “immersed” . The extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions.Due to its diverse nature and composition, the ECM can serve many functions, such as providing support, segregating tissues from one another, and regulating intercellular communication.
Extracellular matrix 1. EXTRACELLULAR MATRIX OHENEBA HAGAN 2. It is the set of extracellular materials that are part of a tissue . This lecture introduces the materials lying outside the cell, known collectively as the extracellular matrix (ECM). Extracellular matrix (MEC). There is no one matrix though, with different tissues having their own specific ECM, which may be dynamic or static in structure. Extracellular Matrix Antonia Jameson Jordan, D.V.M., Ph.D. November 21, 2008 Outline: • Overview of structural and signaling roles of ECM • Two main classes of ECM molecules – Glycosaminoglycan polysaccharide chains • Structure and function – Fibrous proteins • Structure and function • Basal lamina (basement membrane) • Integrins 1
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Extracellular Matrix lecture 1.