5% (1030 proteins) of all human proteins have been experimentally detected in the golgi apparatus by the Human Protein Atlas.285 proteins in the golgi apparatus are supported by experimental evidence and out of these 75 proteins are enhanced by the Human Protein Atlas. Golgi and amyloid plaque formation. ; 774 proteins in the golgi apparatus have multiple locations. The Golgi apparatus is responsible for sorting, modifying, and shipping off the products that come from the rough ER, much like a post-office. The Golgi apparatus is a series of membranes shaped like pancakes. The membrane surrounds an area of fluid where the complex molecules (proteins, sugars, enzymes) are stored and changed. The Golgi apparatus, or Golgi complex, functions as a factory in which proteins received from the ER are further processed and sorted for transport to their eventual destinations: lysosomes, the plasma membrane, or secretion. ; 111 proteins in the golgi apparatus show a cell to cell variation. Golgi apparatus is a stack of flattened membrane bound vesicles that functions in the storage, modification and repackaging of manufactured biochemical substances in the cell. This organelle was discovered by an Italian scientist called Camillo Golgi while investigating the nervous system in 1879, the organelle was named after him in 1898. The Golgi apparatus looks like stacked flattened discs, almost like stacks of oddly shaped pancakes. One neuropathological hallmark of AD is the formation of extracellular amyloid plaques by secreted amyloid beta (Aβ) peptides (Nelson et al., 2009), which is highly related to Golgi structure and function (Figure (Figure1). The single membrane is similar to the cell membrane in that it has two layers.
The Golgi Apparatus. Like the ER, these discs are membranous.